Clinical Trials & Research Projects

NAMI NJ compiles statewide and nationwide research projects and clinical trials related to mental disorders.  Potential participants should contact listed contact person for the specific project or trial. Recruiting agencies can contact Aruna Rao, NAMI NJ Associate Director, at for submission details.



Family Perspective and Involvement in Supported Employment

If you are a family member of someone with a mental illness who has, or is, receiving supported employment, you may be eligible for the following study: Family members are invited to participate in a study exploring your involvement in employment services and your views of the quality of these services. Time commitment to the study is approximately 90 minutes. For more information, please call: 1-609-204-2942. Your participation will be confidential.

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Examining Persistence in Smokers with Schizophrenia

We thought you would want to know about a research study we are doing at 317 George Street in New Brunswick. This is a study for people like you who have schizophrenia or schizoaffective disorder, and who smoke. If you qualify for the study, you will receive free counseling, free nicotine patches, and up to $100 over about 4 months. This page describes what is involved. Call us and we can tell you more, or you can bring this paper to your case manager, nurse, or psychiatrist and they can help you call us.

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Research Opportunity on Supported Education

We are currently recruiting for our Supported Education study which focuses on supporting students who are going to college with a mental health condition. Do you know a student who is struggling to manage school while having a mental health condition? Students in our research may get to work with someone who can help with finding resources on campus, making a wellness plan for when things get tough, improving relationships with others, and setting goals. Everyone enrolled in the study gets information to help with identifying academic interests and skills, learning to pay for education, talking about a disability at school, and finding resources and supports to succeed in school.

For more information you can contact Alison Weigl at or by phone at 215-204-3230 if you have any questions.

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Caregivers Invited for Stress Research Survey

Tyler Corson, a doctoral student in the Gerontology Department at Virginia Commonwealth University and a NAMI family member in Virginia Beach, is working on a research study about caregiver stress.  If you are a caregiver for a person with serious mental illness, and you are age 18 or older, you are invited to participate in an anonymous online survey that takes about 15 minutes to complete.  The survey includes questions about mental illness stigma and your thoughts about providing care.  Your participation in this survey will help us gather information that may be helpful in designing programs to reduce caregiver stress.  Tyler will share the research results with NAMI when the study is complete.

If you have any questions about the survey or would like additional information about the research project, please contact Tyler Corson at  You may also contact Dr. Tracey Gendron, project supervisor, at the VCU Department of Gerontology at (804) 828-1565, or

Please follow this link to the survey:


Study of Brain Function During Simple Tasks and Rest
This NIH funded study focuses on brain activity during the performance of simple
tasks and at “rest” (not engaged in any specific task). Our goal is to understand
how various brain regions are activated and how those regions influence one
another while the brain is at “work” and at “rest.”

We are seeking adult individuals, 18 years or older, who have a diagnosis of
autism or schizophrenia.

This study involves magnetic imaging (MRI) of participants. Consequently,
participants must:
1. be free of any embedded metal (e.g., surgical screws, pace makers, stents,
etc.) or extensive dental work involving metal.
2. be able to remove any piercings, earrings, or other jewelry before scanning
3. be comfortable with being in small spaces
4. not pregnant

Participating involves approximately 50 minutes in the scanner and participants
will be compensated with $50 cash.

For further information please go to:


Interactions of persons with serious mental illness and their relatives

Have you been diagnosed with a mental illness?  Are you willing to spend 20 minutes taking an online research survey?  Participants will be entered to win 1 of 15 $50 electronic gift cards to either Amazon or Walmart. Researchers at the University of Pennsylvania are seeking participants to complete an online survey about the interactions they have with the adult relative with whom they spend the most time.  Help would be greatly appreciated!  For more information or if you would like to take the survey please click on the link below.   If you have any questions please send an email to the student investigator, Travis Labrum, at

Rutgers University Research Study: Seeking Loved Ones & Caregivers of Individuals Diagnosed with Schizophrenia, Schizoaffective Disorder, or Bipolar Disorder

(1) Residing in the New Jersey, New York, or Philadelphia area
(2) Access to computer or tablet with internet
(3) Participants and their loved ones must be over the age of 18 and be in contact with each other 2-3x per week or living together

Study involves 3 phone questionnaire appointments – Participants receive a $10 Amazon Gift Card per phone questionnaire

For more information or to sign up as a participant, please contact our research assistant: Victoria Martin, Rutgers UBHC, 151 Centennial Avenue, Piscataway NJ 08854, Tel: 908 705 5413,


How romantic partners communicate when one or both people are depressed

Do you have depression? Are you in a relationship with someone who has depression? Researchers from the University of Illinois are conducting a study to better understand how romantic partners communicate when one or both people are depressed.

You are eligible to participate in the study if:

(1) You are in a romantic relationship,
(2) You and/or your partner have been professionally diagnosed with depression,
(3) Both partners are willing to participate in the study,
(4) Both partners are 18 years of age or older, and
(5) Both partners have their own email account.

Participation involves completing an online questionnaire, which takes approximately 45 to 60 minutes to complete. All couples who complete the study will receive $20 in Amazon e-gift cards ($10 to each partner). If BOTH partners are willing to participate, send an email to with:

(a) your name and email address,
(b) your partner’s name and email address, and
(c) who has been diagnosed with depression (you, your partner, or both).


The National Center for Advancing Translational Sciences Seeks Input for its Strategic Plan
NCATS will hold a series of informational webinars to facilitate the feedback process on November 4 and 10, 2016.

Want to Help the FDA? Become a Consumer Representative on an FDA Advisory Committee

The FDA continually seeks input from consumers on scientific and medical issues by including Consumer Representatives on Agency advisory committees. The role of Consumer Representatives is to: represent the consumer perspective on issues and actions before the advisory committee; serve as a liaison between the committee and interested consumers, associations, coalitions, and consumer organizations; and, facilitate dialogue with the advisory committees on scientific issues that affect consumers. Learn about current and upcoming vacancies on FDA advisory committees.


Bipolar Disorder (Pediatric) Research Study

Treatment of Severe Mood Dysregulation, SMD

(Inpatient: 12- to 15 weeks) This study tests the efficacy of different treatments for decreasing irritability in children with severe mood and behavioral problems. Participants have symptoms of severe irritability and are not doing well on their current medications. The child must be currently in treatment with a physician, medically healthy and not currently hospitalized, psychotic or suicidal. The study includes day or full hospitalization to discontinue medication, followed by either methylphenidate plus citalopram, or methylphenidate plus placebo. Recruiting ages 7-17. [09-M-0034]

For more information on research conducted by the National Institute of Mental Health in Bethesda, MD click here.


NIH Bipolar & Severe Irritability Research Studies: Enrolling Participants Nationwide

Do You Have A Child with Bipolar Disorder or Severe Irritability?

At the NIH Clinical Center in Bethesda, Maryland, several research studies are being conducted into the causes of bipolar disorder and severe mood dysregulation (SMD). These studies seek children and adolescent participants who have bipolar disorder or severe irritability.

All evaluations, research procedures, inpatient (day or full hospitalization) and outpatient visits are free of cost. Both parent and child must agree to the child’s participation. Schooling is provided during inpatient care. Children and parents are compensated for participation. Travel and lodging expenses are paid by NIMH.

Bipolar Disorder

Those eligible to participate must be ages 6-17, have bipolar disorder and be able to perform research tasks including neuroimaging, computer tasks, and neuropsychological tasks.

This is an outpatient descriptive study using brain imaging and clinical assessment. Study participation begins with an initial outpatient evaluation that lasts one day. Subsequently, testing and brain imaging occur at visits which last two-three days, occur every year, and continue until age 25. Phone contact occurs every six months in between visits.

Severe Irritability

Those eligible to participate must be: ages 7-17; displaying symptoms of chronic anger, sadness, or irritability, as well as hyperarousal (such as insomnia, distractibility, hyperactivity) and extreme responses to frustration (such as frequent, severe temper tantrums); able to perform research tasks that include neuroimaging, computer tasks and neuropsychological testing. Participants must currently be in treatment with a physician, medically healthy, and not currently hospitalized, psychotic, or suicidal.

Non-Treatment Study: This is an outpatient descriptive study using brain imaging and clinical assessment. Study participation begins with an initial outpatient evaluation that lasts one day. Subsequently, testing and brain imaging occur at visits which last two-three days, occur every two years, and continue until age 25. Phone contact occurs every six months in between visits.

Treatment Study: If unstable on current medications participant receives day or full hospitalization to discontinue medication and participate in a 12- to 15-week study of the efficacy of methylphenidate plus citalopram, vs methylphenidate plus placebo, for decreasing irritability in children with severe mood and behavioral problems. (If clinically appropriate, participants who received methylphenidate plus placebo will be offered the opportunity to receive methylphenidate plus citalopram at the end of the study.)

To find out about study criteria and qualifications, or for more information, please call (301 496-8381) or email us at

Posted: October 27, 2015

Does Schizophrenia Run in Your Family?
Research shows that in families with a history of schizophrenia, there is a strong genetic link associated with the disease. A genetic link means that it may be possible for medical science to find the gene or sequence of genes causing this debilitating disorder. This information could then be used to develop new treatments for managing symptoms and to hopefully one day find a cure.

The VA Boston Healthcare System has launched a study using the latest research technology in human DNA analysis to help determine the underlying genetic variables responsible for schizophrenia. To qualify for this study, there must be at least 3 available members of the extended family who are diagnosed with one of these disorders:

– Schizophrenia
– Schizoaffective Disorder
– Schizotypal Personality Disorder
– Bipolar Disorder with Psychotic Features

The study also seeks 3 “healthy” members of the family who are willing to participate. All family members must be at least 18 years old. The study involves a clinical interview and a blood draw. Participants who complete the study receive $130. Study is not restricted to veterans, but is open to the general public.

To learn more, contact:
Paul Nelson, M.Ed.
Study Coordinator
or call 845-981-9514

Posted: October 8, 2014


Randomized Controlled Trial (RCT) of a Motivational Decision Support System (RCTEDSS)
Up to 80% of people with schizophrenia and schizoaffective disorders smoke – a rate that is four times the rate in the general population. Cessation treatments are effective, but these smokers don’t use them. In order to provide an easy-to-use, cost-effective strategy to engage this group of smokers into effective treatments, we developed a single-session, web-based, motivational decision support system, Let’s Talk About Smoking. The system incorporates features that insure high usability among those who can’t use current websites due to cognitive impairments and low computer skills. It provides compelling content that engages users into evidence-based cessation treatments. Read more…

Inclusion Criteria: 18-60 years old; DSM-IV-TR diagnosis psychotic disorder; in treatment at participating mental health center; current daily smoker; fluent in English; physically able to use computer; willing and able to give informed consent.

Exclusion Criteria: past 2 weeks use of evidence based cessation treatment; psychiatric instability; current alcohol or drug dependence; pregnant or nursing.

Rutgers-UNDMJ, New Brunswick, New Jersey
Contact: Williams
Principal Investigator: Jill Williams, MD

Received: August 2014


(Outpatient: 1-2 days) This study examines the role genes play in schizophrenia. Eligible participants have a diagnosis of schizophrenia and no serious drug or alcohol abuse. If possible, the siblings and/or parents of the individuals are invited for interviews and blood donation. Travel and lodging assistance may be available. Recruiting ages 18-55. [95-M-0150]

National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services.
For more information on research conducted by the National Institute of Mental Health in Bethesda, MD click here

Posted: June 1, 2014


NIH Research Studies: Bipolar Disorder & Severe Irritability Symptoms
Enrolling Nationwide, Eligible Participants Ages 6-17

How do the brain and the symptoms change as children grow up?

Researchers will describe over time the moods and behavior of children use specialized testing and brain imaging to learn about specific brain changes associated with bipolar disorder or severe irritability in children. Studies involve 1-5 outpatient visits, with follow up visits as the child grows up. All clinical evaluations, research procedures, and outpatient visits are free of cost. Children and parents are compensated for participation. Travel and lodging expenses are paid by NIMH.

Participants must have a bipolar diagnosis, or have symptoms of severe irritability. Irritability symptoms include: difficulty handling frustration (severe temper tantrums and rages) and “hyper” behavior (distractible, hyperactive, trouble sleeping).

Call for more information and eligibility criteria.

301-496-8381 or TTY: 1-866-411-1010

Email: or

Updated: May 27, 2014


(Inpatient: 3 weeks & 4-6 months) This study investigates the causes and treatment of childhood psychotic disorders that start prior to age 12. Thorough evaluations are provided including genetic studies, and further participation in a drug treatment sub-study is optional. Currently recruiting ages 6-18. [89-M-0006]
National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services.
For more information on research conducted by the National Institute of Mental Health in Bethesda, MD click here

Posted: April 1, 2014



Clinical – a service of the U.S. National Institutes of Health and a weblink to identify clinical trials seeking participants. Find clinical trials by state on

National Recruitment: Join NIH Depression Research Studies

Does depression impede your daily life? Are you currently feeling sad and hopeless, experiencing worthlessness and guilt, and have a lack of interest in everyday activities you once enjoyed? NIH studies are investigating the brain and experimental medications (such as ketamine and diazoxide) to rapidly reduce depressive symptoms.  Research includes: depressed adults ages 18 to 70, outpatient visits or inpatient stays of up to 12 weeks at the NIH Clinical Center in Bethesda, MD.  Call 1-877-MIND-NIH, TTY: 1-866-411-1010, Email: