Clinical Trials & Research Projects

NAMI NJ compiles statewide and nationwide research projects and clinical trials related to mental illness. NAMI NJ does not accept financial compensation for recruiting clinical trial participants, nor do we endorse any products or treatments. Inquires should be directed to the listed contact person for the specific project or trial. Recruiting agencies can send project details to for posting approval.



Alcohol Treatment and Research Program

The Rutgers Alcohol Treatment and Research Program is looking for participants who are 18 years or older and have a drinking problem they would like to change. The program offers free alcohol treatment as well as up to $200 for complete study participation. Anyone who is interested could call (848) 932-8080 for more information.

Visit the website:

Download flyer


Clinical Trial, Adolescent Schizophrenia 

This study is looking at whether a medication called brexpiprazole is safe and effective in reducing the symptoms of schizophrenia in youth aged 13-17. Brexpiprazole has already been approved by the FDA to treat symptoms of schizophrenia in adults. The goal of this study is to increase treatment options for youth with schizophrenia.

Participants may be eligible for this study if they:

  • Are 13-17 years old
  • Have a current, confirmed diagnosis of schizophrenia
  • Have experienced symptoms of schizophrenia for at least 6 months prior to joining the study

There will be approximately 400 people participating in this study world-wide.

This study will take place at approximately 45 clinic sites across the USA. Please visit the study website to view clinic sites in your region.

Download NAMI flyer


Clinical Trial, Major Depressive Disorder

This study is looking at whether a medication called brexpiprazole is safe and effective in reducing the symptoms of major depressive disorder (MDD) when used together with other antidepressant therapies. The goal of this study is to increase treatment options for adults with MDD who have difficulty managing their symptoms with current antidepressant therapies.

Participants may be eligible for this study if they:

Are 18-65 years old
Have a current diagnosis of major depressive disorder (MDD), and are having difficulty managing symptoms
Are taking one or two antidepressant therapies as recommended by a healthcare provider

There will be approximately 1,500 people participating in this study in the USA.

This study will take place at approximately 75 clinic sites across the USA. Please visit the study website to view clinic sites in your region.

If you have questions or would like more information, please refer to the study website:

Download Flyer


Rutgers UBHC – Feasibility study of the ability of ERG components to distinguish schizophrenia and bipolar disorder type I.

This is an evaluation study of the back of the eye, or retina, to flashes of light using a test called an electroretinogram (ERG). No medication or intervention is involved.

  • People within the age range of 18-50 and a diagnosis of Schizophrenia or Bipolar I Disorder may be eligible.

  • The study involves 4 appointments each about 1-2 hours, including the use of interviews and ERG testing.

  • Participants will be compensated at $20/hour for each appointment; transportation costs are paid for by the study.

For more information, or to see if you qualify, please call Nancy Tiffany at (732) 235-4592

Download flyer


Volunteers Wanted: View flyer 1, 2, 3

Help us understand the needs of individuals who suffer from trauma-associated sleep disorders

To participate in the survey, click here:

By taking the survey, you will help us advance the use of technological solutions for real-time monitoring of individuals who have trauma-related sleep disorders, in order to develop new treatments. The goal of the survey is to understand individual preference for Mobile application, home and wearable sensor devices used as treatment for people with sleep difficulties.The survey is open to adults who use smartphone App’s and self-report some difficulty with sleep. Please note adults may participate in this survey whether or not they have a brain disorder.

The survey takes about 10 minutes to complete and there is no cost to participate. It is confidential and anonymous. Your name and personal information are not collected. You can also help us by sharing this page with firends or relative of yours who might have sleep problems.

For more information, you can contact our research team:

You can also visit us at:


Depression, TMS, Psychotherapy and Brain Function

This study seeks depressed participants to test effects of the combination of repetitive transcranial magnetic stimulation (TMS) and psychotherapy on brain function.

This study is enrolling eligible adults ages 18-65 with major depressive disorder, who are free of other serious medical conditions. If you are currently taking anti-depressants, you may still be eligible.

This inpatient and/or outpatient study involves daily visits for 8 weeks followed by once-monthly visits for 3 months. Participation includes research evaluations, brain scans, and active TMS and psychotherapy, or inactive TMS and psychotherapy. Those who received inactive TMS may receive active TMS after the experimental phase is completed. After completing the study, participants receive short-term care at the NIH while transitioning back to a provider. The 3 monthly follow up visits can be conducted via telephone.

All clinical evaluations, research tasks and visits are free of cost. Participants are compensated for research procedures. The study is conducted at the NIH in Bethesda, Maryland, and is enrolling participants nationwide, from across the United States. Travel arrangements are provided and costs are covered by NIMH (arrangements vary by distance).

To find out if you qualify, or for more information email or call 1-877-MIND-NIH (1-877-646-3644), TTY: 1-866-411-1222.


The SleepWell Consortium

The SleepWell Consortium is a research collaboration between the non-profit foundations Cohen Veterans Bioscience and Early Signal, and MyHealios, a corporation. This collaboration will advance the study and use of home and wearable sensor devices for real-time monitoring of individuals affected by trauma-associated sleep disorders.

Real-time, individualized monitoring may improve diagnosis and management of neuropsychiatric conditions. Currently, there is a lack the tools to offer patients such individualized monitoring. At the time of diagnosis, it is often too late to provide effective treatment. The use of wearables and other devices may increase the availability and adherence to treatment yielding better patient outcomes.To better understand the needs of individuals with trauma-associated sleep disorders, share the opportunity to participate in a new online survey. The survey is open to adults who use smartphone APPs and self-report difficulty with sleep. Adults may participate in this survey whether or not they have a brain disorder.

The study is supported by a research grant from Cohen Veterans Bioscience.

Participants can take the study by visiting

For more information, go to or email

Download the flyer


Understanding Depression in Teenagers, NIH Research Study

Join a research study seeking to understand the causes of depression in teenagers. As part of a larger study looking at mood dysregulation, participation begins with an initial 1-day outpatient evaluation. Research visits may include annual outpatient visits up to age 25, and/or 4- to 15-week inpatient treatment.

This part of the study is currently recruiting medically healthy teenagers, ages 12-17, who meet the criteria for major depressive disorder and are in treatment with a provider in their community. The study may include assessments, research testing, brain imaging, and standard medications, cognitive-behavioral therapy, psychological testing.

Enrollment is from across the United States. Transportation expenses to NIH in Bethesda, MD are reimbursed. There is no cost to participate, compensation is provided.

Call 1-301-496-8381 [TTY: 1-866-411-1010] or Email


Examining Persistence in Smokers With Schizophrenia

Rutgers University is conducting a research study designed to help smokers with schizophrenia quit smoking. They provide free counseling and free nicotine patches. If you are an adult smoker with schizophrenia or schizoaffective disorder between the ages of 18 and 64, you may qualify to participate in this study. Participants are paid up to $100 over 4 months and receive free counseling and nicotine patches. If interested, please email Jessica Ortiz at

Download the flyer

Learn more


How Clinical Disorders Change Visual Perception

Researchers from University Behavioral Health Care are looking for volunteers for a research study on how clinical disorders change visual perception. People with a diagnosis of schizophrenia or bipolar disorder, and people with no psychiatric history may be eligible to participate.

– The study involves about 3 – 4 visits each lasting between 1 to 3 hours
– Participants will complete a psychiatric interview. They will also lie inside a medical imaging (fMRI) scanner as they make judgments about what is seen on a screen. (The study involves no treatment or medication.)
– Participants will be paid between $20 – $30 per hour and could earn a total of $180-$290.
– Transportation costs will be covered for some participants.
– If eligible, some participants may receive a picture of their own brains.

For more information, please call Caren Alexander at (732) 235-9297

Download the flyer


SND111 Study: Clinical Research Study on Adolescent Schizophrenia

The SND111 study is looking at whether an investigational medication called NaBen® (Sodium Benzoate) is safe and effective in improving symptoms of schizophrenia in teenagers.

The goal of this study is to increase treatment options available for teenagers with schizophrenia.

Download the flyer / Download the brochure


Participate in a Sandy Recovery Focus Group

The Sandy recovery research team from Rutgers University and NYU is recruiting young adults and teens, as well as parents, to join a single, 60-minute focus group exploring the long-term effects of Hurricane Sandy.

We are looking for people who…
– Are between the ages of 15-22 (one young adult per household);
– Were significantly affected by Hurricane Sandy;
– Lived in one of the following counties in New Jersey at the time of Sandy: Atlantic, Bergen, Cape May, Essex, Hudson, Middlesex, Monmouth, Ocean, or Union.

Download the flyer


Family Perspective and Involvement in Supported Employment

If you are a family member of someone with a mental illness who has, or is, receiving supported employment, you may be eligible for the following study: Family members are invited to participate in a study exploring your involvement in employment services and your views of the quality of these services. Time commitment to the study is approximately 90 minutes. For more information, please call: 1-609-204-2942. Your participation will be confidential.

Download the flyer


Research Opportunity on Supported Education

We are currently recruiting for our Supported Education study which focuses on supporting students who are going to college with a mental health condition. Do you know a student who is struggling to manage school while having a mental health condition? Students in our research may get to work with someone who can help with finding resources on campus, making a wellness plan for when things get tough, improving relationships with others, and setting goals. Everyone enrolled in the study gets information to help with identifying academic interests and skills, learning to pay for education, talking about a disability at school, and finding resources and supports to succeed in school.

For more information you can contact Alison Weigl at or by phone at 215-204-3230 if you have any questions.

Download the flyer


Caregivers Invited for Stress Research Survey

Tyler Corson, a doctoral student in the Gerontology Department at Virginia Commonwealth University and a NAMI family member in Virginia Beach, is working on a research study about caregiver stress.  If you are a caregiver for a person with serious mental illness, and you are age 18 or older, you are invited to participate in an anonymous online survey that takes about 15 minutes to complete.  The survey includes questions about mental illness stigma and your thoughts about providing care.  Your participation in this survey will help us gather information that may be helpful in designing programs to reduce caregiver stress.  Tyler will share the research results with NAMI when the study is complete.

If you have any questions about the survey or would like additional information about the research project, please contact Tyler Corson at  You may also contact Dr. Tracey Gendron, project supervisor, at the VCU Department of Gerontology at (804) 828-1565, or

Please follow this link to the survey:


Study of Brain Function During Simple Tasks and Rest
This NIH funded study focuses on brain activity during the performance of simple
tasks and at “rest” (not engaged in any specific task). Our goal is to understand
how various brain regions are activated and how those regions influence one
another while the brain is at “work” and at “rest.”

We are seeking adult individuals, 18 years or older, who have a diagnosis of
autism or schizophrenia.

This study involves magnetic imaging (MRI) of participants. Consequently,
participants must:
1. be free of any embedded metal (e.g., surgical screws, pace makers, stents,
etc.) or extensive dental work involving metal.
2. be able to remove any piercings, earrings, or other jewelry before scanning
3. be comfortable with being in small spaces
4. not pregnant

Participating involves approximately 50 minutes in the scanner and participants
will be compensated with $50 cash.

For further information please go to:


Interactions of persons with serious mental illness and their relatives

Have you been diagnosed with a mental illness?  Are you willing to spend 20 minutes taking an online research survey?  Participants will be entered to win 1 of 15 $50 electronic gift cards to either Amazon or Walmart. Researchers at the University of Pennsylvania are seeking participants to complete an online survey about the interactions they have with the adult relative with whom they spend the most time.  Help would be greatly appreciated!  For more information or if you would like to take the survey please click on the link below.   If you have any questions please send an email to the student investigator, Travis Labrum, at

Rutgers University Research Study: Seeking Loved Ones & Caregivers of Individuals Diagnosed with Schizophrenia, Schizoaffective Disorder, or Bipolar Disorder

(1) Residing in the New Jersey, New York, or Philadelphia area
(2) Access to computer or tablet with internet
(3) Participants and their loved ones must be over the age of 18 and be in contact with each other 2-3x per week or living together

Study involves 3 phone questionnaire appointments – Participants receive a $10 Amazon Gift Card per phone questionnaire

For more information or to sign up as a participant, please contact our research assistant: Victoria Martin, Rutgers UBHC, 151 Centennial Avenue, Piscataway NJ 08854, Tel: 908 705 5413,


How romantic partners communicate when one or both people are depressed

Do you have depression? Are you in a relationship with someone who has depression? Researchers from the University of Illinois are conducting a study to better understand how romantic partners communicate when one or both people are depressed.

You are eligible to participate in the study if:

(1) You are in a romantic relationship,
(2) You and/or your partner have been professionally diagnosed with depression,
(3) Both partners are willing to participate in the study,
(4) Both partners are 18 years of age or older, and
(5) Both partners have their own email account.

Participation involves completing an online questionnaire, which takes approximately 45 to 60 minutes to complete. All couples who complete the study will receive $20 in Amazon e-gift cards ($10 to each partner). If BOTH partners are willing to participate, send an email to with:

(a) your name and email address,
(b) your partner’s name and email address, and
(c) who has been diagnosed with depression (you, your partner, or both).


The National Center for Advancing Translational Sciences Seeks Input for its Strategic Plan
NCATS will hold a series of informational webinars to facilitate the feedback process on November 4 and 10, 2016.

Want to Help the FDA? Become a Consumer Representative on an FDA Advisory Committee

The FDA continually seeks input from consumers on scientific and medical issues by including Consumer Representatives on Agency advisory committees. The role of Consumer Representatives is to: represent the consumer perspective on issues and actions before the advisory committee; serve as a liaison between the committee and interested consumers, associations, coalitions, and consumer organizations; and, facilitate dialogue with the advisory committees on scientific issues that affect consumers. Learn about current and upcoming vacancies on FDA advisory committees.


Bipolar Disorder (Pediatric) Research Study

Treatment of Severe Mood Dysregulation, SMD

(Inpatient: 12- to 15 weeks) This study tests the efficacy of different treatments for decreasing irritability in children with severe mood and behavioral problems. Participants have symptoms of severe irritability and are not doing well on their current medications. The child must be currently in treatment with a physician, medically healthy and not currently hospitalized, psychotic or suicidal. The study includes day or full hospitalization to discontinue medication, followed by either methylphenidate plus citalopram, or methylphenidate plus placebo. Recruiting ages 7-17. [09-M-0034]

For more information on research conducted by the National Institute of Mental Health in Bethesda, MD click here.


NIH Bipolar & Severe Irritability Research Studies: Enrolling Participants Nationwide

Do You Have A Child with Bipolar Disorder or Severe Irritability?

At the NIH Clinical Center in Bethesda, Maryland, several research studies are being conducted into the causes of bipolar disorder and severe mood dysregulation (SMD). These studies seek children and adolescent participants who have bipolar disorder or severe irritability.

All evaluations, research procedures, inpatient (day or full hospitalization) and outpatient visits are free of cost. Both parent and child must agree to the child’s participation. Schooling is provided during inpatient care. Children and parents are compensated for participation. Travel and lodging expenses are paid by NIMH.

Bipolar Disorder

Those eligible to participate must be ages 6-17, have bipolar disorder and be able to perform research tasks including neuroimaging, computer tasks, and neuropsychological tasks.

This is an outpatient descriptive study using brain imaging and clinical assessment. Study participation begins with an initial outpatient evaluation that lasts one day. Subsequently, testing and brain imaging occur at visits which last two-three days, occur every year, and continue until age 25. Phone contact occurs every six months in between visits.

Severe Irritability

Those eligible to participate must be: ages 7-17; displaying symptoms of chronic anger, sadness, or irritability, as well as hyperarousal (such as insomnia, distractibility, hyperactivity) and extreme responses to frustration (such as frequent, severe temper tantrums); able to perform research tasks that include neuroimaging, computer tasks and neuropsychological testing. Participants must currently be in treatment with a physician, medically healthy, and not currently hospitalized, psychotic, or suicidal.

Non-Treatment Study: This is an outpatient descriptive study using brain imaging and clinical assessment. Study participation begins with an initial outpatient evaluation that lasts one day. Subsequently, testing and brain imaging occur at visits which last two-three days, occur every two years, and continue until age 25. Phone contact occurs every six months in between visits.

Treatment Study: If unstable on current medications participant receives day or full hospitalization to discontinue medication and participate in a 12- to 15-week study of the efficacy of methylphenidate plus citalopram, vs methylphenidate plus placebo, for decreasing irritability in children with severe mood and behavioral problems. (If clinically appropriate, participants who received methylphenidate plus placebo will be offered the opportunity to receive methylphenidate plus citalopram at the end of the study.)

To find out about study criteria and qualifications, or for more information, please call (301 496-8381) or email us at

Posted: October 27, 2015

Does Schizophrenia Run in Your Family?
Research shows that in families with a history of schizophrenia, there is a strong genetic link associated with the disease. A genetic link means that it may be possible for medical science to find the gene or sequence of genes causing this debilitating disorder. This information could then be used to develop new treatments for managing symptoms and to hopefully one day find a cure.

The VA Boston Healthcare System has launched a study using the latest research technology in human DNA analysis to help determine the underlying genetic variables responsible for schizophrenia. To qualify for this study, there must be at least 3 available members of the extended family who are diagnosed with one of these disorders:

– Schizophrenia
– Schizoaffective Disorder
– Schizotypal Personality Disorder
– Bipolar Disorder with Psychotic Features

The study also seeks 3 “healthy” members of the family who are willing to participate. All family members must be at least 18 years old. The study involves a clinical interview and a blood draw. Participants who complete the study receive $130. Study is not restricted to veterans, but is open to the general public.

To learn more, contact:
Paul Nelson, M.Ed.
Study Coordinator
or call 845-981-9514

Posted: October 8, 2014


Randomized Controlled Trial (RCT) of a Motivational Decision Support System (RCTEDSS)
Up to 80% of people with schizophrenia and schizoaffective disorders smoke – a rate that is four times the rate in the general population. Cessation treatments are effective, but these smokers don’t use them. In order to provide an easy-to-use, cost-effective strategy to engage this group of smokers into effective treatments, we developed a single-session, web-based, motivational decision support system, Let’s Talk About Smoking. The system incorporates features that insure high usability among those who can’t use current websites due to cognitive impairments and low computer skills. It provides compelling content that engages users into evidence-based cessation treatments. Read more…

Inclusion Criteria: 18-60 years old; DSM-IV-TR diagnosis psychotic disorder; in treatment at participating mental health center; current daily smoker; fluent in English; physically able to use computer; willing and able to give informed consent.

Exclusion Criteria: past 2 weeks use of evidence based cessation treatment; psychiatric instability; current alcohol or drug dependence; pregnant or nursing.

Rutgers-UNDMJ, New Brunswick, New Jersey
Contact: Williams
Principal Investigator: Jill Williams, MD

Received: August 2014


(Outpatient: 1-2 days) This study examines the role genes play in schizophrenia. Eligible participants have a diagnosis of schizophrenia and no serious drug or alcohol abuse. If possible, the siblings and/or parents of the individuals are invited for interviews and blood donation. Travel and lodging assistance may be available. Recruiting ages 18-55. [95-M-0150]

National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services.
For more information on research conducted by the National Institute of Mental Health in Bethesda, MD click here

Posted: June 1, 2014


NIH Research Studies: Bipolar Disorder & Severe Irritability Symptoms
Enrolling Nationwide, Eligible Participants Ages 6-17

How do the brain and the symptoms change as children grow up?

Researchers will describe over time the moods and behavior of children use specialized testing and brain imaging to learn about specific brain changes associated with bipolar disorder or severe irritability in children. Studies involve 1-5 outpatient visits, with follow up visits as the child grows up. All clinical evaluations, research procedures, and outpatient visits are free of cost. Children and parents are compensated for participation. Travel and lodging expenses are paid by NIMH.

Participants must have a bipolar diagnosis, or have symptoms of severe irritability. Irritability symptoms include: difficulty handling frustration (severe temper tantrums and rages) and “hyper” behavior (distractible, hyperactive, trouble sleeping).

Call for more information and eligibility criteria.

301-496-8381 or TTY: 1-866-411-1010

Email: or

Updated: May 27, 2014


(Inpatient: 3 weeks & 4-6 months) This study investigates the causes and treatment of childhood psychotic disorders that start prior to age 12. Thorough evaluations are provided including genetic studies, and further participation in a drug treatment sub-study is optional. Currently recruiting ages 6-18. [89-M-0006]
National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services.
For more information on research conducted by the National Institute of Mental Health in Bethesda, MD click here

Posted: April 1, 2014



Clinical – a service of the U.S. National Institutes of Health and a weblink to identify clinical trials seeking participants. Find clinical trials by state on

National Recruitment: Join NIH Depression Research Studies

Does depression impede your daily life? Are you currently feeling sad and hopeless, experiencing worthlessness and guilt, and have a lack of interest in everyday activities you once enjoyed? NIH studies are investigating the brain and experimental medications (such as ketamine and diazoxide) to rapidly reduce depressive symptoms.  Research includes: depressed adults ages 18 to 70, outpatient visits or inpatient stays of up to 12 weeks at the NIH Clinical Center in Bethesda, MD.  Call 1-877-MIND-NIH, TTY: 1-866-411-1010, Email: